Cat. No.: IBDA-433451
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Online InquiryTarget Information
| Target Name | FLAP |
| Uniprot ID | P20292 |
| Cellular Localization | Nucleus membrane. Endoplasmic reticulum membrane. |
| Immunogen | Synthetic peptide: C-HKVEHESRTQNGR , corresponding to internal sequence amino acids 28-40 of Human FLAP. |
| Function | Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. |
Product Details
| Description | Goat polyclonal antibody to FLAP. |
| Host Species | Goat |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide: C-HKVEHESRTQNGR , corresponding to internal sequence amino acids 28-40 of Human FLAP. |
| Positive Control | WB: Human U937 cell lysate. |
| Application | WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Upon delivery aliquot. Store at -20 °C or -80 °C |
| Storage Buffer | pH: 7.30 Preservative: 0.02% Sodium Azide Constituent: 0.5% BSA, 0.5% Tris Buffered Saline |
| Handling | Avoid freeze-thaw cycles. |