Floxuridine

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Cat. No.: IBDI-437970

Floxuridine (5-Fluorouracil 2'-deoxyriboside) is a pyrimidine analog and known as an oncology antimetabolite. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage by activating the ATM and ATR checkpoint signaling pathways in vitro. Floxuridine is a extreamly potent inhibitor for S. aureus infection and induces cell apoptosis. Floxuridine has antiviral effects against HSV and CMV.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	Nucleoside Antimetabolite/Analog \| DNA/RNA Synthesis \| Bacterial \| CMVHSV \| Apoptosis
Molecular Weight	246.19
Appearance	Solid
Synonyms	5-Fluorouracil 2'-deoxyriboside
SMILES	OC[[email protected]@H]1[[email protected]@H](O)C[[email protected]](N2C(NC(C(F)=C2)=O)=O)O1
Purity	99.95%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.