FLT3-IN-11

Cat. No.: IBDI-434031

FLT3-IN-11 (compound 30) is a potent, selective and orally active FLT3 kinase inhibitor with IC50s of 7.22 nM and 4.95 nM for wild-type FLT3 and FLT3-D835Y, respectively. FLT3-IN-11 high selectivity for FLT3 over c-KIT (>1000-fold). FLT3-IN-11has excellent anti-acute myeloid leukemia (AML) activity (MV4-11 cells, IC50 of 3.2 nM).

Product Details

Target	FLT3
Molecular Weight	422.45
SMILES	FC(F)(F)C(C(N[[email protected]@H]1CC[[email protected]@H](CC1)N)=N2)=CN=C2NC3=CC=C(C=C3)C(N(C)C)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.