FLT3/ITD-IN-2

Cat. No.: IBDI-435266

FLT3/ITD-IN-2 (Compound 17) is a potent FLT3 internal tandem duplications (FLT3-ITD) inhibitor with IC50 values of 0.3, 0.4 and 1.0 nM against FLT3 D835Y, FLT3 and FLT3-ITD, respectively. FLT3/ITD-IN-2 potently inhibits the phosphorylation of FLT3 and displays excellent antiproliferative activities against acute myeloid leukemia cell lines.

Product Details

Target	FLT3
Molecular Weight	489.49
SMILES	O=C(C1=C2N=C(C=CN2N=C1)N[[email protected]@H]3CCCNC3)NC4=CC=C(C=C4C(F)(F)F)N5CCOCC5

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.