Cat. No.: IBDA-435141
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Online InquiryTarget Information
| Target Name | FMNL1 |
| Uniprot ID | O95466 |
| Cellular Localization | Cytoplasm > cell cortex. Cell projection > bleb. Colocalized with F-actin in bleb protrusions and Cytoplasm. Cell membrane. Cytoplasmic vesicle > phagosome. Recruited to actin-rich phagosomes during phagocytosis. Translocates to the plasma membrane upon activation by RAC1. |
| Immunogen | Recombinant fragment corresponding to Human FMNL1 aa 850-1000. |
| Function | May play a role in the control of cell motility and survival of macrophages (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. |
Product Details
| Description | Rabbit polyclonal antibody to FMNL1. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment corresponding to Human FMNL1 aa 850-1000. |
| Positive Control | WB: MOLT-4 cell lysate. ICC/IF: U-2 OS cells. IHC-P: Human lung, lymph node and small intestine tissue. |
| Application | ICC/IF, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.02% Sodium Azide Constituent: 40% Glycerol, PBS |
| Handling | Avoid freeze-thaw cycles. |