Cat. No.: IBDA-435140
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Online InquiryTarget Information
| Target Name | FMNL1 |
| Uniprot ID | O95466 |
| Cellular Localization | Cytoplasm > cell cortex. Cell projection > bleb. Colocalized with F-actin in bleb protrusions and Cytoplasm. Cell membrane. Cytoplasmic vesicle > phagosome. Recruited to actin-rich phagosomes during phagocytosis. Translocates to the plasma membrane upon activation by RAC1. |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 631 - 873 of Human FMNL1. |
| Function | May play a role in the control of cell motility and survival of macrophages (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. |
Product Details
| Description | Rabbit polyclonal antibody to FMNL1. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 631 - 873 of Human FMNL1. |
| Positive Control | 293T, A431, HepG2, MOLT4 and Raji cell lysates. H1299 and HeLa whole cell lysate |
| Application | WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Upon delivery aliquot. Store at -20 °C or -80 °C |
| Storage Buffer | pH: 7 Preservative: 0.01% Thimerosal (Merthiolate) Constituent: 1.21% Tris, 0.75% Glycine, 10% Glycerol |
| Handling | Avoid freeze-thaw cycles. |