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Forodesine hydrochloride

Cat. No.: IBDI-437041

Forodesine hydrochloride (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride is a potent human lymphocyte proliferation inhibitor. Forodesine hydrochloride could induce apoptosis in leukemic cells by increasing the dGTP levels.

Size (Solid):

Product Details

Target Nucleoside Antimetabolite/Analog | Apoptosis
Molecular Weight 302.71
Appearance Solid
Synonyms BCX-1777 hydrochloride, Immucillin-H hydrochloride
SMILES O=C1C(NC=C2[[email protected]@H]3N[[email protected]](CO)[[email protected]@H](O)[[email protected]]3O)=C2NC=N1.Cl
Purity 99.34%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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