Forodesine

Cat. No.: IBDI-437040

Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels.

Product Details

Target	Nucleoside Antimetabolite/Analog | Apoptosis
Molecular Weight	266.25
Appearance	Solid
Synonyms	BCX-1777, Immucillin-H
SMILES	O=C1C(NC=C2[[email protected]@H]3N[[email protected]](CO)[[email protected]@H](O)[[email protected]]3O)=C2NC=N1

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.