Forskolin

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Cat. No.: IBDI-431107

Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase. Forskolin is also an inducer of intracellular cAMP formation. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	Adenylate Cyclase \| FXR \| \| Autophagy
Molecular Weight	410.50
Appearance	Solid
Synonyms	Coleonol, Colforsin, HL 362
SMILES	O=C1[[email protected]@]2(O)[[email protected]]([[email protected]@H](OC(C)=O)[[email protected]@H](O)[[email protected]@]3([H])C(C)(C)CC[[email protected]](O)[[email protected]@]32C)(C)O[[email protected]@](C)(C=C)C1
Structure Classification	Terpenoids>Diterpenoids
Purity	99.64%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.