Fulvestrant-d3

Cat. No.: IBDI-432286

Fulvestrant-d3 is the deuterium labeled Fulvestrant. Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy.

Product Details

Target	Estrogen Receptor/ERR | Autophagy | Apoptosis
Molecular Weight	609.79
Synonyms	ICI 182780-d3, ZD 9238-d3, ZM 182780-d3
SMILES	C[[email protected]@]12[[email protected]](O)([2H])C([2H])([2H])C[[email protected]@]1([H])[[email protected]]3([H])[[email protected]](CCCCCCCCCS(CCCC(F)(F)C(F)(F)F)=O)CC4=C(C=CC(O)=C4)[[email protected]@]3([H])CC2

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.