Fusicoccin

Cat. No.: IBDI-431060

Fusicoccin (Fusicoccin A), a fungal pytotoxin, is a stabilizer of specific 14-3-3 protein-protein interactions. Fusicoccin sabilizes H +-ATPase/14-3-3 cmplex in pants, maintaining the enzyme in activated state. Fusicoccin also stabilizes 14-3-3 protein interactions with binding partners containing a C-terminal 14-3-3 recognition motif (a mode 3 motif), such as ERα, GPIbα, TASK3, CTFR, and p53. Fusicoccin induces apoptosis in cancer cells and has anticancer activity.

Product Details

Target	Apoptosis
Molecular Weight	680.82
Appearance	Solid
Synonyms	Fusicoccin A
SMILES	C[[email protected]](/C=C([[email protected]]1COC)\[[email protected]](CC1)([H])[[email protected]]2C)([[email protected]]3O)C([[email protected]]([[email protected]@H]2O)O[[email protected]@H](O[[email protected]@H]4COC(C)(C)C=C)[[email protected]@H]([[email protected]]([[email protected]@H]4O)OC(C)=O)O)=C(C3)[[email protected]](C)COC(C)=O
Structure Classification	Terpenoids>Diterpenoids
Purity	96.20%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.