Cat. No.: IBDP-532205
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Online InquiryTarget Information
| Synonyms | Ac-LPSDDLEFWCHVMY-NH2 |
| Sequence | Ac-LPSDDLEFWCHVMY-NH2 |
| Function | Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) is a potent peptide antagonist of FZD7 receptors , selectively binds to FZD7 CRD subclass and alters the conformation of the CRD and the architecture of its lipid-binding groove. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively. Fz7-21 impairs the function of FZD7 in Wnt–β-catenin signalling and stem cell function in intestinal organoids. |
Product Details
| Product Type | Peptide |
| Cas | 2247635-23-8 |
| Molecular Weight | 1796.05 kDa |
Storage & Handling
| Shipping | Shipped at Room Temperature. |
| Storage | Store at -20 °C or -80 °C. |
| Handling | Avoid freeze / thaw cycle. |