Galantide

Target Information

Sequence

GWTLNSAGYLLGPQQFFGLM-NH2

Function

Galantide, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P. Galantide recognizes two classes of galanin binding sites (KD<0.1 nM and ~6 nM) in the rat hypothalamus. Galantide dose dependently (IC50=1.0 nM) antagonizes the galanin-mediated inhibition of the glucose-induced insulin secretion from mouse pancreatic islets. Galantide appears to bind to a single population of SP receptors (KD~40 nM).

Product Details

Product Type	Peptide
Cas	138579-66-5
Molecular Weight	2199.53 kDa

Storage & Handling

Shipping	Shipped at Room Temperature.
Storage	Store at -20 °C or -80 °C.
Handling	Avoid freeze / thaw cycle.