Ganoderic acid D

Cat. No.: IBDI-431306

Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells. Ganoderic acid D induces HeLa human cervical carcinoma apoptosis.

Product Details

Target	Sirtuin | Apoptosis
Molecular Weight	514.65
Appearance	Solid
SMILES	CC1(C)C(CC[[email protected]]2(C)C3=C([[email protected]@]4(C(C[[email protected]@H]([[email protected]]4(CC3=O)C)[[email protected]](C)CC(CC(C)C(O)=O)=O)=O)C)[[email protected]@H](O)C[[email protected]@]12[H])=O
Structure Classification	Terpenoids>Triterpenes
Purity	99.81%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.