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Ginsenoside Rd

Cat. No.: IBDI-431249

Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC50 of 12.05±0.82 μM in HepG2 cells. Ginsenoside Rd inhibits expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca 2+ influx. Ginsenoside Rd inhibits CYP2D6, CYP1A2, CYP3A4, and CYP2C9, with IC50s of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM, and 85.1±9.1 μM, respectively.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target NF-κB | COX | Calcium Channel | Cytochrome P450 | Endogenous Metabolite
Molecular Weight 947.15
Appearance Solid
Synonyms Gypenoside VIII
SMILES C[[email protected]](CC/C=C(C)/C)([[email protected]]1([H])[[email protected]]([[email protected]](O)C[[email protected]@]2([H])[[email protected]@]3(C)CC[[email protected]]4([H])[[email protected]]2(C)CC[[email protected]](O[[email protected]]5([H])O[[email protected]](CO)[[email protected]@H](O)[[email protected]](O)[[email protected]]5O[[email protected]]6([H])O[[email protected]](CO)[[email protected]@H](O)[[email protected]](O)[[email protected]]6O)C4(C)C)([H])[[email protected]@]3(C)CC1)O[[email protected]@H]7O[[email protected]](CO)[[email protected]@H](O)[[email protected]](O)[[email protected]]7O
Structure Classification Terpenoids>Triterpenes
Purity 98.02%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.