GKA50 quarterhydrate

Cat. No.: IBDI-435400

GKA50 quarterhydrate is a potent glucokinase activator (EC50=33 nM at 5 mM glucose) and stimulates insulin release from mouse islets of Langerhans. GKA50 quarterhydrate is a glucose-like activator of beta-cell metabolism in rodent and human islets and a Ca 2+-dependent modulator of insulin secretion. GKA50 quarterhydrate shows significant glucose lowering in high fat fed female rats.

Product Details

Target	Glucokinase
Molecular Weight	469.01
Appearance	Solid
SMILES	O=C(C1=CC=C(NC(C2=CC(O[[email protected]@H](C)CC3=CC=CC=C3)=CC(O[[email protected]@H](C)COC)=C2)=O)N=C1)O.[1/4].O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.