GNE-4997

Cat. No.: IBDI-435691

GNE-4997 is a potent and selective interleukin-2-inducible T-cell kinase (ITK) inhibitor with a Ki of 0.09 nM, and the correlation between the basicity of solubilizing elements in GNE-4997 and off-target antiproliferative effects reduces cytotoxicity.

Product Details

Target	Itk
Molecular Weight	515.58
SMILES	O=C(C1=NNC2=C1C[[email protected]](C3(F)F)[[email protected]@]3(C)C2)NC4=CN([[email protected]](C5=CC=CC=C5)[[email protected]@H]6S(CCCC6)(=O)=O)N=C4

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.