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GSK143 dihydrochloride

Cat. No.: IBDI-431917

GSK143 dihydrochloride is an orally active and highly selective spleen tyrosine kinase (SYK) inhibitor with a pIC50 of 7.5. GSK143 dihydrochloride inhibits phosphorylated Erk (pErk: pIC50=7.1). GSK143 dihydrochloride reduces inflammation and prevents recruitment of immune cells in the intestinal muscularis in mice.

Size (Solid):

Product Details

Target Syk | PERK
Molecular Weight 415.32
Appearance Solid
SMILES [H]Cl.[H]Cl.O=C(C1=CN=C(N[[email protected]]2[[email protected]@H](N)COCC2)N=C1NC3=CC=C(C)C=C3)N
Purity 99.73%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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