GSK143

Cat. No.: IBDI-435582

GSK143 is an orally active and highly selective spleen tyrosine kinase (SYK) inhibitor with a pIC50 of 7.5. GSK143 inhibits phosphorylated Erk (pErk: pIC50=7.1). GSK143 reduces inflammation and prevents recruitment of immune cells in the intestinal muscularis in mice.

Product Details

Target	Syk | PERK
Molecular Weight	342.40
SMILES	O=C(C1=CN=C(N[[email protected]]2[[email protected]@H](N)COCC2)N=C1NC3=CC=C(C)C=C3)N

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.