hCAIX-IN-10

Cat. No.: IBDI-437293

hCAIX-IN-10 (Compound 6i) is a selective carbonic anhydrase IX and XII inhibitor with Ki s of 61.5 and 586.8 nM for hCA IX and hCA XII, respectively.  hCA IX and hCA XII are transmembrane isoforms which have been characterized as biomarkers for several types of tumors. The hCA XII assists in maintenance of acid-base homoeostasis in normal as well as tumor cells.

Product Details

Target	Carbonic AnhydRase
Molecular Weight	479.55
SMILES	O=C1N(C2=CC=CC(C)=C2)C(C3=CN(C4=CC=CC=C4)N=C3C5=CC6=CC=CC=C6OC5=O)SC1

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.