HDAC3/6-IN-2

Cat. No.: IBDI-436305

HDAC3/6-IN-2 (compound 15) is a potent HDAC6 and HDAC3 inhibitor, with IC50 values of 0.368 and 0.635 μM, respectively. HDAC3/6-IN-2 shows antitumor activity, and induces cancer cell apoptosis. HDAC3/6-IN-2 decreases the levels of HDAC6 and HDAC3, associated with upregulation of acetylated H3 and α-tubulin.

Product Details

Target	HDAC | Apoptosis
Molecular Weight	822.09
SMILES	O=C(NC1=CC=C(N2CCN(C([[email protected]](CC[[email protected]]3(C)CC[[email protected]@]4(C)[[email protected]]5(C)CCC6C(C)(C)C(C(C#N)=C[[email protected]]6(C)C57)=O)(C)C[[email protected]@]3([H])C4=CC7=O)=O)CC2)C=C1)CCCCCCC(NO)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.