HDAC6-IN-5

Cat. No.: IBDI-435361

HDAC6-IN-5 (compound 11b) is a potent and BBB-penetrated HDAC6 inhibitor, with an IC50 of 0.025 μM. HDAC6-IN-5 exhibits strong inhibitory activity against Aβ1-42 self-aggregation and AChE, with IC50 values of 3.0 and 0.72 μM. HDAC6-IN-5 can enhance neurite outgrowth without significant neurotoxicity.

Product Details

Target	HDAC | Amyloid-β | CholinesteRase (ChE)
Molecular Weight	408.25
SMILES	O=C(C1=CC=C(C=C1)NC2=C3C=CC=CC3=NC4=CC=C(C=C42)Br)NO

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.