hGGPPS-IN-3

Cat. No.: IBDI-435307

hGGPPS-IN-3 (Compound 13h) is a potent inhibitor of the human geranylgeranyl pyrophosphate synthase (hGGPPS). hGGPPS-IN-3 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs). hGGPPS-IN-3 induces target-selective apoptosis of multiple myeloma (MM) cells and exhibits antimyeloma activity in vivo.

Product Details

Target	Apoptosis
Molecular Weight	613.31
SMILES	O=C(C1=CC(C2=NC3=C(C(NC(P(O)(O)=O)P(O)(O)=O)=N2)C=CS3)=CC=C1)NC4=CC(Br)=C(C=C4)C

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.