HIV-1 inhibitor-24

Cat. No.: IBDI-434251

HIV-1 inhibitor-24 (compound S-12a) is a highly potent HIV-1 reverse transcriptase, with an IC50 value of 9.5 nM. HIV-1 inhibitor-24 has high antiretroviral activity against WT HIV-1 with an EC50 of 1.6 nM, and exhibits relatively low cytotoxicity with a CC50 of 9.07 μM in MT-4 cells. HIV-1 inhibitor-24 is well tolerated at a dose of 2 g/kg in mice and has a significant cardiovascular safety.

Product Details

Target	HIV
Molecular Weight	433.46
SMILES	N#CC1=CC=C(C2=CC=C([[email protected]@H](C3=NC(NC4=CC=C(C#N)C=C4)=NC=C3)O)C(OC)=C2)C=C1

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.