Horse IL-1 alpha ELISA kit

Overview

Sample Type	Cell culture supernatant, Serum, Plasma
Detection Method	Colorimetric
Assay Type	Sandwich (quantitative)
Assay Duration	Multiple steps standard assay
Product Type	Macrophage / Inflamm.
Sensitivity	0.82 pg/ml
Range	0.82 pg/ml - 200 pg/ml
Species Reactivity	Reacts with: Horse
Platform	Pre-coated microplate (12 x 8 well strips)

Target

Function	Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Sequence Similarities	Belongs to the IL-1 family.
Cellular Localization	Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
Domain	The similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.

Storage & Handling

Storage	Store at +4°C.
Storage Buffer	Constituent: 100% PBS