HPK1-IN-33

Cat. No.: IBDI-434232

HPK1-IN-33 (compound 21) is a potent Hematopoietic Progenitor Kinase 1 (HPK1) inhibitor with a Ki value of 1.7 nM. HPK1-IN-33 inhibits the produce of IL-2 with EC50s of 286, >10000 nM in Jurkat WT and Jurkat HPK1 KO cells, respectively.

Product Details

Target	MAP4K
Molecular Weight	370.81
SMILES	N#CC1=CC(C2=C(NC3=NC=NC(N4CC[[email protected]]([[email protected]](C4)N)F)=C32)Cl)=CC=C1

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.