Human CD59 Antibody Pair - BSA and Azide free

Overview

Assay Type	ELISA set
Product Type	Cell Type Markers
Range	23.438 pg/ml - 1500 pg/ml
Species Reactivity	Reacts with: Rat, Human
Platform	Reagents
Application	Sandwich ELISA

Properties

Carrier Free

Yes

Target

Function	Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
Sequence Similarities	Contains 1 UPAR/Ly6 domain.
Cellular Localization	Cell membrane. Secreted. Soluble form found in a number of tissues.

Storage & Handling

Storage	Store at +4°C.
Storage Buffer	Constituent: 100% PBS