Human Ficolin-2 Antibody Pair - BSA and Azide free

Overview

Assay Type	ELISA set
Product Type	Secreted Molecules
Range	46.875 pg/ml - 3000 pg/ml
Species Reactivity	Reacts with: Human
Platform	Reagents
Application	Sandwich ELISA

Properties

Carrier Free

Yes

Target

Function	May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region.
Tissue Specificity	Expressed by the liver and secreted in plasma.
Sequence Similarities	Belongs to the ficolin lectin family. Contains 1 collagen-like domain. Contains 1 fibrinogen C-terminal domain.
Cellular Localization	Secreted.
Domain	The fibrinogen-like domain (FBG) contains potential calcium-binding sites that may be involved in carbohydrate binding.

Storage & Handling

Storage	Store at +4°C.
Storage Buffer	Constituent: 100% PBS