Human Ficolin-2 ELISA Kit

Overview

Sample Type	Serum, Cell culture media, Hep Plasma, EDTA Plasma
Detection Method	Colorimetric
Assay Type	Sandwich (quantitative)
Assay Time	1 h 30 min
Assay Duration	One step assay
Product Type	Secreted Molecules
Sensitivity	8.35 pg/ml
Range	46.88 pg/ml - 3000 pg/ml
Species Reactivity	Reacts with: Human
Platform	Pre-coated microplate (12 x 8 well strips)

Target

Function	May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region.
Tissue Specificity	Expressed by the liver and secreted in plasma.
Sequence Similarities	Belongs to the ficolin lectin family. Contains 1 collagen-like domain. Contains 1 fibrinogen C-terminal domain.
Cellular Localization	Secreted.
Domain	The fibrinogen-like domain (FBG) contains potential calcium-binding sites that may be involved in carbohydrate binding.

Storage & Handling

Storage

Store at +4°C. Please refer to protocols.