Human ICAM1 ELISA Set (without plates)

Overview

Sample Type	Cell culture supernatant, Serum, Plasma
Assay Type	Sandwich (quantitative)
Assay Duration	Multiple steps standard assay
Product Type	Cell Type Markers
Sensitivity	< 0.1 ng/ml
Range	0.25 ng/ml - 8 ng/ml
Species Reactivity	Reacts with: Human
Platform	Reagents
Application	Sandwich ELISA

Target

Function	ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Sequence Similarities	Belongs to the immunoglobulin superfamily. ICAM family. Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Cellular Localization	Membrane.

Storage & Handling

Storage	Store at +4°C.
Storage Buffer	Constituent: 100% PBS