Human IRAK4 ELISA Kit, Fluorescent

Overview

Sample Type	Cell culture extracts, Tissue Extracts
Detection Method	Fluorescent
Assay Type	Sandwich (quantitative)
Assay Time	1 h 30 min
Assay Duration	One step assay
Product Type	TLR Signaling
Sensitivity	137 pg/ml
Range	0.25 ng/ml - 64 ng/ml
Species Reactivity	Reacts with: Human
Platform	Pre-coated microplate (12 x 8 well strips)

Target

Function	Required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1.
Sequence Similarities	Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily. Contains 1 death domain. Contains 1 protein kinase domain.

Storage & Handling

Storage

Store at +4°C. Please refer to protocols.