Human IRAK4 ELISA Kit

Overview

Sample Type	Cell culture extracts, Tissue Extracts
Detection Method	Colorimetric
Assay Type	Sandwich (quantitative)
Assay Time	1 h 30 min
Assay Duration	One step assay
Product Type	TLR Signaling
Sensitivity	247.4 pg/ml
Range	0.5 ng/ml - 32 ng/ml
Species Reactivity	Reacts with: Human
Platform	Pre-coated microplate (6 x 8 well strips)

Target

Function	Required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1.
Sequence Similarities	Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily. Contains 1 death domain. Contains 1 protein kinase domain.

Storage & Handling

Storage

Please refer to protocols.