Human MIP5 ELISA Kit

Overview

Sample Type	Cell culture supernatant, Serum, Cell culture extracts, Other biological fluids, Tissue Extracts, Hep Plasma, EDTA Plasma, Cit plasma
Detection Method	Colorimetric
Assay Type	Sandwich (quantitative)
Assay Time	1 h 30 min
Assay Duration	One step assay
Product Type	Chemokines
Sensitivity	27.1 pg/ml
Range	89.4 pg/ml - 1500 pg/ml
Species Reactivity	Reacts with: Human Does not react with: Cow
Platform	Pre-coated microplate (12 x 8 well strips)

Target

Function	Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15.
Tissue Specificity	Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are found in high levels in synovial fluids from rheumatoid patients.
Sequence Similarities	Belongs to the intercrine beta (chemokine CC) family.
Cellular Localization	Secreted.

Storage & Handling

Storage

Store at +4°C. Please refer to protocols.