Cat. No.: IBDAK-620687
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| Assay Type | ELISA set |
| Product Type | Cell Type Markers |
| Range | 39 pg/ml - 2500 pg/ml |
| Species Reactivity | Reacts with: Human |
| Platform | Reagents |
| Application | Sandwich ELISA |
Properties
| Carrier Free | Yes |
Target
| Function | Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. |
| Tissue Specificity | Natural killer cells. Expressed on essentially all CD56+CD3- NK cells from freshly isolated PBMC. Also detected in gamma-delta cells and CD8+ alpha-beta T-cells. Expressed in interferon-producing killer dendritic cells (IKDCs). |
| Sequence Similarities | Contains 1 C-type lectin domain. |
| Cellular Localization | Membrane. |
Storage & Handling
| Storage | Store at +4°C. Please refer to protocols. |