Human PD-L1 ELISA Kit, fluorescent

Overview

Sample Type	Urine, Serum, Cell culture extracts, Cell culture media, Hep Plasma, EDTA Plasma, Cit plasma
Detection Method	Fluorescent
Assay Type	Sandwich (quantitative)
Assay Time	1 h 30 min
Assay Duration	One step assay
Product Type	Cell Type Markers
Sensitivity	1.04 pg/ml
Range	1.95 pg/ml - 4000 pg/ml
Species Reactivity	Reacts with: Human
Platform	Microplate (12 x 8 well strips)

Target

Function	Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Tissue Specificity	Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes.
Sequence Similarities	Belongs to the immunoglobulin superfamily. BTN/MOG family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Cellular Localization	Cell membrane and Endomembrane system.

Storage & Handling

Storage

Store at -20°C. Please refer to protocols.