Human RALBP1 Antibody Pair - BSA and Azide free

Overview

Assay Type	ELISA set
Product Type	TLR Signaling
Species Reactivity	Reacts with: Human
Platform	Reagents
Application	Sandwich ELISA

Properties

Carrier Free

Yes

Target

Function	Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
Tissue Specificity	Expressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes.
Sequence Similarities	Contains 1 Rho-GAP domain.
Cellular Localization	Membrane.

Storage & Handling

Storage	Store at +4°C.
Storage Buffer	Constituent: 100% PBS