Human TREM2 Antibody Pair - BSA and Azide free

Overview

Assay Type	ELISA set
Product Type	Macrophage / Inflamm.
Range	78.1 pg/ml - 5000 pg/ml
Species Reactivity	Reacts with: Human
Platform	Reagents
Application	Sandwich ELISA

Properties

Carrier Free

Yes

Target

Function	May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.
Tissue Specificity	Expressed on macrophages and dendritic cells but not on granulocytes or monocytes. In the CNS strongest expression seen in the basal ganglia, corpus callosum, medulla oblongata and spinal cord.
Sequence Similarities	Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Cellular Localization	Secreted and Cell membrane.

Storage & Handling

Storage	Store at +4°C.
Storage Buffer	Constituent: 100% PBS