Human TREM2 ELISA Kit

Overview

Sample Type	Serum, Cell culture extracts, Tissue Extracts, Cell culture media, Hep Plasma, EDTA Plasma, Cit plasma, Cerebral Spinal Fluid
Detection Method	Colorimetric
Assay Type	Sandwich (quantitative)
Assay Time	1 h 30 min
Assay Duration	One step assay
Product Type	Macrophage / Inflamm.
Sensitivity	10.5 pg/ml
Range	78.1 pg/ml - 5000 pg/ml
Species Reactivity	Reacts with: Human Does not react with: Cow
Platform	Pre-coated microplate (12 x 8 well strips)

Target

Function	May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.
Tissue Specificity	Expressed on macrophages and dendritic cells but not on granulocytes or monocytes. In the CNS strongest expression seen in the basal ganglia, corpus callosum, medulla oblongata and spinal cord.
Sequence Similarities	Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Cellular Localization	Secreted and Cell membrane.

Storage & Handling

Storage

Store at +4°C. Please refer to protocols.