Cat. No.: IBDA-432439
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Online InquiryTarget Information
| Target Name | Iba1 |
| Uniprot ID | P55008 |
| Cellular Localization | Cytoplasm > cytoskeleton. Cell projection > ruffle membrane. Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. |
| Immunogen | The details of the immunogen for this antibody are not available. |
| Function | Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. |
Product Details
| Description | Mouse monoclonal antibody to Iba1 - Chimeric – BSA and Azide Free. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Rat, Human |
| Immunogen | The details of the immunogen for this antibody are not available. |
| Positive Control | WB: THP-1 whole cell lysate. IHC-P: Human cerebrum, Human endometrium and Mouse cerebrum, Rat cerebrum tissues. ICC: THP-1 cells. Flow Cyt: THP-1 cell. IP: THP-1 cell. |
| Application | Flo, ICC/IF, IHC-P, IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C |
| Storage Buffer | pH: 7.2 Constituent: 100% PBS |
| Handling | Do not freeze. |