Cat. No.: IBDA-432443
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Online InquiryTarget Information
Target Name | Iba1 |
Uniprot ID | P55008 |
Cellular Localization | Cytoplasm > cytoskeleton. Cell projection > ruffle membrane. Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. |
Immunogen | Synthetic peptide. |
Function | Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. |
Product Details
Description | Rabbit monoclonal antibody to Iba1 - BSA and Azide Free. |
Host Species | Rabbit |
Clonality | Monoclonal |
Purity | Protein A purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Synthetic peptide. |
Positive Control | WB: THP-1 cell lysate. Flow Cyt (Intra): K-562 cells. ICC/IF: Jurkat cells. IHC-P: Human kidney, Human tonsil, human glioma and Human cerebrum tissues. |
Application | Flo, ICC/IF, IHC-P, WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at 4 °C |
Storage Buffer | pH: 7.20 Constituent: 100% PBS |
Handling | Do not freeze. |