Iba1 Monoclonal Antibody - BSA and Azide Free

Target Information

Target Name	Iba1
Uniprot ID	P55008
Cellular Localization	Cytoplasm > cytoskeleton. Cell projection > ruffle membrane. Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
Immunogen	Synthetic peptide.
Function	Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Product Details

Description	Rat monoclonal antibody to Iba1 - Chimeric – BSA and Azide Free.
Host Species	Rat
Clonality	Monoclonal
Purity	Ion Exchange Chromatography
Isotype	IgG2a
Conjugation	Unconjugated
Reactivity	Mouse, Rat, Human
Immunogen	Synthetic peptide.
Positive Control	IHC-P: Human tonsil. cerebrum, and liver. Mouse cerebrum and liver. Rat cerebrum and liver. Flow Cyt. intr. : MCF7 (Human breast adenocarcinoma epithelial cell) / THP-1 (Human monocytic leukemia monocyte.
Application	Flo, IHC-P

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at 4 °C
Storage Buffer	pH: 7.2 Constituent: 100% PBS
Handling	Avoid freeze-thaw cycles.