Cat. No.: IBDA-432437
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Online InquiryTarget Information
Target Name | Iba1 |
Uniprot ID | P55008 |
Cellular Localization | Cytoplasm > cytoskeleton. Cell projection > ruffle membrane. Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. |
Immunogen | Synthetic peptide. |
Function | Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. |
Product Details
Description | Goat monoclonal antibody to Iba1 - Chimeric – BSA and Azide Free. |
Host Species | Goat |
Clonality | Monoclonal |
Purity | Ion Exchange Chromatography |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Mouse, Rat, Human |
Immunogen | Synthetic peptide. |
Positive Control | IHC-P: Human tonsil, Human liver, Human cerebrum, Mouse liver, Mouse cerebrum, Rat liver and Rat cerebrum tissues. ICC/IF: THP-1 cells. Flow Cyt (Intra): THP-1 cells |
Application | Flo, ICC/IF, IHC-P |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at 4 °C |
Storage Buffer | pH: 7.20 Constituent: 100% PBS |
Handling | Do not freeze. |