Iba1 Monoclonal Antibody

Target Information

Target Name	Iba1
Uniprot ID	P55008
Cellular Localization	Cytoplasm > cytoskeleton. Cell projection > ruffle membrane. Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
Immunogen	Synthetic peptide.
Function	Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Product Details

Description	Rabbit monoclonal antibody to Iba1.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse, Rat, Human
Immunogen	Synthetic peptide.
Positive Control	WB: HL-60, THP-1, U937, RAW 264.7 and NR8383 whole cell lysates. Human, mouse and rat spleen lysates. Mouse testis and liver lysates. Rat and mouse hippocampus and brain tissue lysates. IHC-P: Human Cerebral cortex, human hippocampus. Rat and mouse normal brain tissues. Flow Cyt (Intra): U937 cells. IHC-Fr: Mouse Cerebral cortex tissue. ICC/IF: Rat hippocampal mixed glia.
Application	Flo, ICC/IF, IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	Preservative: 0.01% Sodium Azide Constituent: 59% PBS, 40% Glycerol, 0.05% BSA
Handling	Avoid freeze-thaw cycles.