Cat. No.: IBDA-432428
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Online InquiryTarget Information
Target Name | Iba1 |
Uniprot ID | P55008 |
Cellular Localization | Cytoplasm > cytoskeleton. Cell projection > ruffle membrane. Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. |
Immunogen | Synthetic peptide. |
Function | Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. |
Product Details
Description | HRP Rabbit monoclonal antibody to Iba1. |
Host Species | Rabbit |
Clonality | Monoclonal |
Purity | Protein A purified |
Isotype | IgG |
Conjugation | HRP |
Reactivity | Human |
Immunogen | Synthetic peptide. |
Positive Control | IHC-P: normal human hippocampus tissue sections |
Application | IHC-P |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Short term: 4 °C. Long term: -20 °C. Store in the dark |
Storage Buffer | pH: 7.40 Preservative: 0.1% Proclin 300 Solution Constituent: 1% BSA, 30% Glycerol, PBS |
Handling | Avoid freeze-thaw cycles. |