Iba1 Monoclonal Antibody

Target Information

Target Name	Iba1
Uniprot ID	P55008
Cellular Localization	Cytoplasm > cytoskeleton. Cell projection > ruffle membrane. Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
Immunogen	Recombinant fragment within Human Iba1 aa 1-146.
Function	Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Product Details

Description	Mouse monoclonal antibody to Iba1.
Host Species	Mouse
Clonality	Monoclonal
Purity	Protein A/G purified
Isotype	IgG1
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Recombinant fragment within Human Iba1 aa 1-146.
Positive Control	IHC-P: Human tonsil tissue.
Application	IHC-P, Protein Array

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.05% Sodium Azide Constituent: PBS, 0.05% BSA
Handling	Avoid freeze-thaw cycles.