Iba1 Monoclonal Antibody

Target Information

Target Name	Iba1
Uniprot ID	P55008
Cellular Localization	Cytoplasm > cytoskeleton. Cell projection > ruffle membrane. Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
Immunogen	Recombinant full length protein corresponding to Human Iba1.
Function	Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Product Details

Description	FITC Mouse monoclonal antibody to Iba1.
Host Species	Mouse
Clonality	Monoclonal
Purity	Immunogen affinity purified
Isotype	IgG2b
Conjugation	FITC
Reactivity	Human
Immunogen	Recombinant full length protein corresponding to Human Iba1.
Positive Control	Flow Cytometry: THP-1 cells.
Application	Flo

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at 4 °C
Storage Buffer	pH: 7.20 Preservative: 0.1% Sodium Azide Constituent: PBS, 1% BSA