Iba1 Polyclonal Antibody

Target Information

Target Name	Iba1
Uniprot ID	P55008
Cellular Localization	Cytoplasm > cytoskeleton. Cell projection > ruffle membrane. Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
Immunogen	Recombinant fragment corresponding to Human Iba1 (internal sequence).
Function	Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Product Details

Description	Rabbit polyclonal antibody to Iba1.
Host Species	Rabbit
Clonality	Polyclonal
Purity	Immunogen affinity purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse, Rat, Human
Immunogen	Recombinant fragment corresponding to Human Iba1 (internal sequence).
Positive Control	WB: Rat and mouse liver extract, THP-1, mouse and rat brain tissue. IHC-P: Rat and mouse brain tissue. Flow: human THP1 cells, murine microglia cells. ICC/IF: human THP-1 cells. IP: human K562 cells
Application	Flo, ICC/IF, IHC-P, IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Upon delivery aliquot. Store at -20 °C or -80 °C
Storage Buffer	pH: 7 Preservative: 0.025% Proclin 300 Constituent: 79% PBS, 20% Glycerol
Handling	Avoid freeze-thaw cycles.