Iba1 Polyclonal Antibody

Target Information

Target Name	Iba1
Uniprot ID	P55008
Cellular Localization	Cytoplasm > cytoskeleton. Cell projection > ruffle membrane. Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
Immunogen	Synthetic peptide corresponding to Human Iba1 aa 135-147 (C terminal).
Function	Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Product Details

Description	Goat polyclonal antibody to Iba1.
Host Species	Goat
Clonality	Polyclonal
Purity	Immunogen affinity purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Rat, Human
Immunogen	Synthetic peptide corresponding to Human Iba1 aa 135-147 (C terminal).
Positive Control	WB: Human lymph node and rat brain tissue lysate. IHC-P: Human spleen tissue.
Application	IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Upon delivery aliquot. Store at -20 °C
Storage Buffer	pH: 7.30 Preservative: 0.02% Sodium Azide Constituent: Tris Buffered Saline, 0.5% BSA
Handling	Avoid freeze-thaw cycles.