Cat. No.: IBDA-434769
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Online InquiryTarget Information
Target Name | ICAM1 |
Uniprot ID | P05362 |
Cellular Localization | Membrane. |
Immunogen | Recombinant fragment within Human ICAM1 aa 300-500 (C terminal). |
Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
Product Details
Description | Rabbit monoclonal antibody to ICAM1 - BSA and Azide Free. |
Host Species | Rabbit |
Clonality | Monoclonal |
Purity | Protein A purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Recombinant fragment within Human ICAM1 aa 300-500 (C terminal). |
Positive Control | IHC-P: Human lung carcinoma and tonsil tissue sections. Flow Cyt (Intra): Ramos cells. ICC/IF: Raji cells. IP: Raji whole cell lysate. WB: HUVEC treated with 10ng/ml for 18 hours and Ramos whole cell lysate. |
Application | Flo, ICC/IF, IHC-P, IP, WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at 4 °C |
Storage Buffer | pH: 7.2 Constituent: PBS |
Handling | Do not freeze. |