Cat. No.: IBDA-434764
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Online InquiryTarget Information
| Target Name | ICAM1 |
| Uniprot ID | P05362 |
| Cellular Localization | Membrane. |
| Immunogen | Tissue, cells or virus corresponding to Human ICAM1. |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
Product Details
| Description | Mouse monoclonal antibody to ICAM1. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Affinity purified |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Tissue, cells or virus corresponding to Human ICAM1. |
| Positive Control | WB: SK N BE, Saos-2 and HT1080 whole cell lysate. Flow Cytometry: HK-2 cells stimulated with TGF-beta1. IHC: Human amniotic membrane tissues. |
| Application | WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C. Store undiluted |
| Storage Buffer | pH: 7.20 Preservative: 0.09% Sodium Azide Constituent: 0.14% Monobasic Dihydrogen Sodium Phosphate, 0.87% Sodium Chloride |
| Handling | Do not freeze. |